Old Trade, New Tricks: Insights into the Spontaneous Mutation Process from the Partnering of Classical Mutation Accumulation Experiments with High-Throughput Genomic Approaches

Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental investigations into the rate and fitness effects of spontaneous mutations are central to the study of evolution. Mutation accumulation (MA) experiments have served as a cornerstone for furthering our understanding...

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Detalles Bibliográficos
Autores principales: Katju, Vaishali, Bergthorsson, Ulfar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330053/
https://www.ncbi.nlm.nih.gov/pubmed/30476040
http://dx.doi.org/10.1093/gbe/evy252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330053/
https://www.ncbi.nlm.nih.gov/pubmed/30476040
http://dx.doi.org/10.1093/gbe/evy252

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