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High resolution genetic mapping of putative causal interactions between regions of open chromatin
Physical interaction of regulatory elements in three-dimensional space poses a challenge for studies of disease because noncoding risk variants may be substantial distances from the genes they regulate. Experimental methods to capture these interactions, such as chromosome conformation capture (3C),...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330062/ https://www.ncbi.nlm.nih.gov/pubmed/30478436 http://dx.doi.org/10.1038/s41588-018-0278-6 |