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Temporal dynamics of bacteria-plasmid coevolution under antibiotic selection
Horizontally acquired genes can be costly to express even if they encode useful traits, such as antibiotic resistance. We previously showed that when selected with tetracycline, Escherichia coli carrying the tetracycline-resistance plasmid RK2 evolved mutations on both replicons that together provid...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330079/ https://www.ncbi.nlm.nih.gov/pubmed/30209344 http://dx.doi.org/10.1038/s41396-018-0276-9 |