Relative impact of indels versus SNPs on complex disease

It is unclear whether insertions and deletions (indels) are more likely to influence complex traits than abundant single‐nucleotide polymorphisms (SNPs). We sought to understand which category of variation is more likely to impact health. Using the SardiNIA study as an exemplar, we characterized 478...

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Detalles Bibliográficos
Autores principales: Gagliano, Sarah A., Sengupta, Sebanti, Sidore, Carlo, Maschio, Andrea, Cucca, Francesco, Schlessinger, David, Abecasis, Gonçalo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330128/
https://www.ncbi.nlm.nih.gov/pubmed/30565766
http://dx.doi.org/10.1002/gepi.22175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330128/
https://www.ncbi.nlm.nih.gov/pubmed/30565766
http://dx.doi.org/10.1002/gepi.22175

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