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Melanocortin Receptor Accessory Protein 2-Induced Adrenocorticotropic Hormone Response of Human Melanocortin 4 Receptor

Melanocortin 4 receptor (MC4R), a canonical melanocyte-stimulating hormone receptor, is the main responsible for monogenic obesity in humans. Previous studies in fish and avian species showed that MC4R becomes an ACTH receptor after interaction with the melanocortin receptor accessory protein 2 (MRA...

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Detalles Bibliográficos
Autores principales: Soletto, Lucia, Hernández-Balfagó, Sergio, Rocha, Ana, Scheerer, Patrick, Kleinau, Gunnar, Cerdá-Reverter, José Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330173/
https://www.ncbi.nlm.nih.gov/pubmed/30652132
http://dx.doi.org/10.1210/js.2018-00370