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Evasion of Classical Complement Pathway Activation on Plasmodium falciparum-Infected Erythrocytes Opsonized by PfEMP1-Specific IgG

Members of the PfEMP1 protein family are expressed on the surface of P. falciparum-infected erythrocytes (IEs), where they contribute to the pathogenesis of malaria and are important targets of acquired immunity. Although the PfEMP1-specific antibody response is dominated by the opsonizing and compl...

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Detalles Bibliográficos
Autores principales: Larsen, Mads Delbo, Quintana, Maria del Pilar, Ditlev, Sisse Bolm, Bayarri-Olmos, Rafael, Ofori, Michael Fokuo, Hviid, Lars, Garred, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330326/
https://www.ncbi.nlm.nih.gov/pubmed/30666256
http://dx.doi.org/10.3389/fimmu.2018.03088