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The Inhibition of Phosphoinositide-3 Kinases Induce Resolution of Inflammation in a Gout Model

Phosphoinositide-3 kinases (PI3Ks) are central signaling enzymes that are involved in many aspects of immune cell function. PI3Kγ and PI3Kδ are the major isoforms expressed in leukocytes. The role of PI3K isoforms in the resolution of inflammation is still poorly understood. Here, we investigated th...

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Detalles Bibliográficos
Autores principales: Galvão, Izabela, Queiroz-Junior, Celso Martins, de Oliveira, Vivian Louise Soares, Pinho, Vanessa, Hirsch, Emilio, Teixeira, Mauro Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330337/
https://www.ncbi.nlm.nih.gov/pubmed/30666201
http://dx.doi.org/10.3389/fphar.2018.01505