SLIMEr: probing flexibility of lipid metabolism in yeast with an improved constraint-based modeling framework

BACKGROUND: A recurrent problem in genome-scale metabolic models (GEMs) is to correctly represent lipids as biomass requirements, due to the numerous of possible combinations of individual lipid species and the corresponding lack of fully detailed data. In this study we present SLIMEr, a formalism f...

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Detalles Bibliográficos
Autores principales: Sánchez, Benjamín J., Li, Feiran, Kerkhoven, Eduard J., Nielsen, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330394/
https://www.ncbi.nlm.nih.gov/pubmed/30634957
http://dx.doi.org/10.1186/s12918-018-0673-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330394/
https://www.ncbi.nlm.nih.gov/pubmed/30634957
http://dx.doi.org/10.1186/s12918-018-0673-8

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