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SLIMEr: probing flexibility of lipid metabolism in yeast with an improved constraint-based modeling framework
BACKGROUND: A recurrent problem in genome-scale metabolic models (GEMs) is to correctly represent lipids as biomass requirements, due to the numerous of possible combinations of individual lipid species and the corresponding lack of fully detailed data. In this study we present SLIMEr, a formalism f...
Autores principales: | Sánchez, Benjamín J., Li, Feiran, Kerkhoven, Eduard J., Nielsen, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330394/ https://www.ncbi.nlm.nih.gov/pubmed/30634957 http://dx.doi.org/10.1186/s12918-018-0673-8 |
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