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Genome-wide analysis of genetic predisposition to Alzheimer’s disease and related sex disparities

BACKGROUND: Alzheimer’s disease (AD) is the most common cause of dementia in the elderly and the sixth leading cause of death in the United States. AD is mainly considered a complex disorder with polygenic inheritance. Despite discovering many susceptibility loci, a major proportion of AD genetic va...

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Detalles Bibliográficos
Autores principales: Nazarian, Alireza, Yashin, Anatoliy I., Kulminski, Alexander M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330399/
https://www.ncbi.nlm.nih.gov/pubmed/30636644
http://dx.doi.org/10.1186/s13195-018-0458-8