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Vps4b heterozygous mice do not develop tooth defects that replicate human dentin dysplasia I

BACKGROUND: Vacuolar protein sorting-associated protein 4B (VPS4B) is a member of the ATP enzyme AAA protein family, and is mainly involved in protein degradation and cell membrane fusion. Recently, a dominant mutation in this gene was identified in human dentin dysplasia type I (DD-I). Herein, we r...

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Detalles Bibliográficos
Autores principales: Hu, Aiqin, Lu, Ting, Chen, Danna, Huang, Jin, Feng, Weiwei, Li, Yanjun, Guo, Dan, Xu, Xiangmin, Chen, Dong, Xiong, Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330468/
https://www.ncbi.nlm.nih.gov/pubmed/30634912
http://dx.doi.org/10.1186/s12863-018-0699-3