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Follistatin-like 1 protects mesenchymal stem cells from hypoxic damage and enhances their therapeutic efficacy in a mouse myocardial infarction model

BACKGROUND: Cell therapy remains the most promising approach against ischemic heart injury. However, poor survival of engrafted cells in ischemic sites diminishes its therapeutic efficacy. Follistatin-like 1 (Fstl1) is documented as a novel pro-survival cardiokine for cardiomyocytes, and it is prote...

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Detalles Bibliográficos
Autores principales: Shen, Han, Cui, Guanghao, Li, Yanqiong, Ye, Wenxue, Sun, Yimin, Zhang, Zihan, Li, Jingjing, Xu, Guiying, Zeng, Xiansheng, Zhang, Yanxia, Zhang, Wencheng, Huang, Zan, Chen, Weiqian, Shen, Zhenya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330478/
https://www.ncbi.nlm.nih.gov/pubmed/30635025
http://dx.doi.org/10.1186/s13287-018-1111-y