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IFNγ and TNFα synergistically induce apoptosis of mesenchymal stem/stromal cells via the induction of nitric oxide

BACKGROUND: Mesenchymal stem/stromal cells (MSCs) have been widely used to treat various inflammatory diseases. The immunomodulatory capabilities of MSCs are usually licensed by inflammatory cytokines and may vary depending on the levels and the types of inflammatory cytokines. However, how the infl...

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Detalles Bibliográficos
Autores principales: Li, Xiaolei, Shang, Bingxue, Li, Ya-nan, Shi, Yufang, Shao, Changshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330503/
https://www.ncbi.nlm.nih.gov/pubmed/30635041
http://dx.doi.org/10.1186/s13287-018-1102-z