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MicroRNA-Based Prophylaxis in a Mouse Model of Cirrhosis and Liver Cancer

Most hepatocellular carcinomas (HCCs) arise in the context of chronic liver disease and/or cirrhosis. Thus, chemoprevention in individuals at risk represents an important but yet unproven approach. In this study, we investigated the ability of microRNA (miRNA)-based molecules to prevent liver cancer...

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Detalles Bibliográficos
Autores principales: Callegari, Elisa, Domenicali, Marco, Shankaraiah, Ram Charan, D’Abundo, Lucilla, Guerriero, Paola, Giannone, Ferdinando, Baldassarre, Maurizio, Bassi, Cristian, Elamin, Bahaeldin K., Zagatti, Barbara, Ferracin, Manuela, Fornari, Francesca, Altavilla, Giuseppe, Blandamura, Stella, Silini, Enrico Maria, Gramantieri, Laura, Sabbioni, Silvia, Negrini, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330511/
https://www.ncbi.nlm.nih.gov/pubmed/30641476
http://dx.doi.org/10.1016/j.omtn.2018.11.018