Cargando…

Interference of DNAJB6/MRJ Isoform Switch by Morpholino Inhibits Replication of HIV-1 and RSV

The molecular chaperon MRJ (DNAJB6) exhibits two splice isoforms that have different roles in human viral infection, but the regulatory mechanism of MRJ isoform expression is yet unclear. In this study, we show that reduction of the polyadenylation factor CstF64 was correlated with the increase of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ko, Shih-Han, Liau, Yi-Jen, Chi, Ya-Hui, Lai, Mei-Ju, Chiang, Yu-Ping, Lu, Chun-Yi, Chang, Luan-Yin, Tarn, Woan-Yuh, Huang, Li-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330513/
https://www.ncbi.nlm.nih.gov/pubmed/30641477
http://dx.doi.org/10.1016/j.omtn.2018.12.001