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Adeno-Associated Viral Vector 2 and 9 Transduction Is Enhanced in Streptozotocin-Induced Diabetic Mouse Retina

Adeno-associated viruses (AAVs) are currently the most popular vector platform technology for ocular gene therapy. While transduction efficiency and tropism of intravitreally administered AAV has been fairly well established in various retinal conditions, its transduction pattern in diabetic retinas...

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Detalles Bibliográficos
Autores principales: Lee, Si Hyung, Yang, Jin Young, Madrakhimov, Sanjar, Park, Ha Yan, Park, Keerang, Park, Tae Kwann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330514/
https://www.ncbi.nlm.nih.gov/pubmed/30666309
http://dx.doi.org/10.1016/j.omtm.2018.11.008