Circulating histone H3 levels in septic patients are associated with coagulopathy, multiple organ failure, and death: a single-center observational study

BACKGROUND: Nuclear histone proteins are released into the extracellular space, and act as major mediators of coagulopathy and remote organ failure in septic animals. However, the circulating histone levels in septic patients have not been precisely quantified. METHODS: Using a novel enzyme-linked i...

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Detalles Bibliográficos
Autores principales: Yokoyama, Yayoi, Ito, Takashi, Yasuda, Tomotsugu, Furubeppu, Hiroaki, Kamikokuryo, Chinatsu, Yamada, Shingo, Maruyama, Ikuro, Kakihana, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330748/
https://www.ncbi.nlm.nih.gov/pubmed/30651722
http://dx.doi.org/10.1186/s12959-018-0190-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330748/
https://www.ncbi.nlm.nih.gov/pubmed/30651722
http://dx.doi.org/10.1186/s12959-018-0190-4

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