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Non-H3 CDR template selection in antibody modeling through machine learning

Antibodies are proteins generated by the adaptive immune system to recognize and counteract a plethora of pathogens through specific binding. This adaptive binding is mediated by structural diversity in the six complementary determining region (CDR) loops (H1, H2, H3, L1, L2 and L3), which also make...

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Detalles Bibliográficos
Autores principales: Long, Xiyao, Jeliazkov, Jeliazko R., Gray, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330961/
https://www.ncbi.nlm.nih.gov/pubmed/30648015
http://dx.doi.org/10.7717/peerj.6179