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Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release

We turnover billions of apoptotic cells daily, and these are removed by professional and non-professional phagocytes via efferocytosis(1). Characterizing the transcriptional program of phagocytes, we discovered a novel solute carrier family (SLC) gene signature (involving 33 SLC members) that is spe...

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Detalles Bibliográficos
Autores principales: Morioka, Sho, Perry, Justin S. A., Raymond, Michael H., Medina, Christopher B., Zhu, Yunlu, Zhao, Liyang, Serbulea, Vlad, Onengut-Gumuscu, Suna, Leitinger, Norbert, Kucenas, Sarah, Rathmell, Jeffrey C., Makowski, Liza, Ravichandran, Kodi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331005/
https://www.ncbi.nlm.nih.gov/pubmed/30464343
http://dx.doi.org/10.1038/s41586-018-0735-5