Accurate diagnosis of mismatch repair deficiency in colorectal cancer using high-quality DNA samples from cultured stem cells

Mismatch repair (MMR)-deficient or microsatellite instability (MSI) colorectal cancer includes two subtypes; Lynch syndrome and sporadic MSI cancer, both of which generate multiple neoantigens due to unrepaired mutations. Although such patients respond very well to immune checkpoint therapy, their d...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamaura, Tadayoshi, Miyoshi, Hiroyuki, Maekawa, Hisatsugu, Morimoto, Tomonori, Yamamoto, Takehito, Kakizaki, Fumihiko, Higasa, Koichiro, Kawada, Kenji, Matsuda, Fumihiko, Sakai, Yoshiharu, Taketo, M. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331025/
https://www.ncbi.nlm.nih.gov/pubmed/30680068
http://dx.doi.org/10.18632/oncotarget.26495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331025/
https://www.ncbi.nlm.nih.gov/pubmed/30680068
http://dx.doi.org/10.18632/oncotarget.26495

Ejemplares similares