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TLR-4/Wnt modulation as new therapeutic strategy in the treatment of glioblastomas

PURPOSE: Glioblastomas are highly aggressive brain tumors. Various pathways are involved in gliomagenesis, among which the Wingless (Wnt) signaling. Dickkopf protein-related protein 3 (Dkk-3) interacts with proteins of Wnt pathwayas inhibitor. The Wnt signaling contributes to activity of the claudin...

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Detalles Bibliográficos
Autores principales: Casili, Giovanna, Caffo, Maria, Campolo, Michela, Barresi, Valeria, Caruso, Gerardo, Cardali, Salvatore M., Lanza, Marika, Mallamace, Raffaella, Filippone, Alessia, Conti, Alfredo, Germanò, Antonino, Cuzzocrea, Salvatore, Esposito, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331030/
https://www.ncbi.nlm.nih.gov/pubmed/30680070
http://dx.doi.org/10.18632/oncotarget.26500