Preparation of stable tau oligomers for cellular and biochemical studies

Increasing evidence suggests that small oligomers are the principal neurotoxic species of tau in Alzheimer's disease and other tauopathies. However, mechanisms of tau oligomer-mediated neurodegeneration are poorly understood. The transience of oligomers due to aggregation can compromise the sta...

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Detalles Bibliográficos
Autores principales: Karikari, Thomas K., Nagel, David A., Grainger, Alastair, Clarke-Bland, Charlotte, Hill, Eric J., Moffat, Kevin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331036/
https://www.ncbi.nlm.nih.gov/pubmed/30315761
http://dx.doi.org/10.1016/j.ab.2018.10.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331036/
https://www.ncbi.nlm.nih.gov/pubmed/30315761
http://dx.doi.org/10.1016/j.ab.2018.10.013

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