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Improved smallest peptides based on positive charge increase of the γ-core motif from PνD(1) and their mechanism of action against Candida species
BACKGROUND: Plant defensins have a hallmark γ-core motif (GXCX(3-9)C) that is related to their antimicrobial properties. The aim of this work was to design synthetic peptides based on the region corresponding to the PvD(1) defensin γ-core that are the smallest amino acid sequences that bear the stro...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331069/ https://www.ncbi.nlm.nih.gov/pubmed/30666103 http://dx.doi.org/10.2147/IJN.S187957 |