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Improved smallest peptides based on positive charge increase of the γ-core motif from PνD(1) and their mechanism of action against Candida species

BACKGROUND: Plant defensins have a hallmark γ-core motif (GXCX(3-9)C) that is related to their antimicrobial properties. The aim of this work was to design synthetic peptides based on the region corresponding to the PvD(1) defensin γ-core that are the smallest amino acid sequences that bear the stro...

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Detalles Bibliográficos
Autores principales:	de Oliveira Mello, Érica, Taveira, Gabriel Bonan, de Oliveira Carvalho, André, Gomes, Valdirene Moreira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331069/ https://www.ncbi.nlm.nih.gov/pubmed/30666103 http://dx.doi.org/10.2147/IJN.S187957

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