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Chemotherapeutic agent 5-fluorouracil increases survival of SOD1 mouse model of ALS
Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease with no cure. Currently there are only two ALS drugs approved by the FDA, both with a limited therapeutic effect. In the search for drug candidates for ALS, we studied the effect of known stem cell mobilizing agents (treatment) and...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331125/ https://www.ncbi.nlm.nih.gov/pubmed/30640943 http://dx.doi.org/10.1371/journal.pone.0210752 |