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Chemotherapeutic agent 5-fluorouracil increases survival of SOD1 mouse model of ALS

Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease with no cure. Currently there are only two ALS drugs approved by the FDA, both with a limited therapeutic effect. In the search for drug candidates for ALS, we studied the effect of known stem cell mobilizing agents (treatment) and...

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Detalles Bibliográficos
Autores principales:	Rando, Amaya, de la Torre, Miriam, Martinez-Muriana, Anna, Zaragoza, Pilar, Musaro, Antonio, Hernández, Sara, Navarro, Xavier, Toivonen, Janne M., Osta, Rosario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331125/ https://www.ncbi.nlm.nih.gov/pubmed/30640943 http://dx.doi.org/10.1371/journal.pone.0210752

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