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Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis
Extracellular matrix (ECM) assembly and remodelling is critical during development and organ morphogenesis. Dysregulation of ECM is implicated in many pathogenic conditions, including cancer. The type II transmembrane serine protease matriptase and the serine protease prostasin are key factors in a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331135/ https://www.ncbi.nlm.nih.gov/pubmed/30601807 http://dx.doi.org/10.1371/journal.pgen.1007882 |