Cargando…

Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis

Extracellular matrix (ECM) assembly and remodelling is critical during development and organ morphogenesis. Dysregulation of ECM is implicated in many pathogenic conditions, including cancer. The type II transmembrane serine protease matriptase and the serine protease prostasin are key factors in a...

Descripción completa

Detalles Bibliográficos
Autores principales: Drees, Leonard, Königsmann, Tatiana, Jaspers, Martin H. J., Pflanz, Ralf, Riedel, Dietmar, Schuh, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331135/
https://www.ncbi.nlm.nih.gov/pubmed/30601807
http://dx.doi.org/10.1371/journal.pgen.1007882