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Celastrol inhibits colorectal cancer through TGF-β1/Smad signaling
BACKGROUND: There are few clinical challenges associated with the treatment of colorectal cancer (CRC). Studies have shown that TGF-β plays a crucial role in CRC. Importantly, celastrol, a major components of the root extract of the traditional Chinese herb Tripterygium wilfordii Hook F, has been sh...
Autores principales: | Jiang, Zhitao, Cao, Qianyu, Dai, Guoliang, Wang, Jianchun, Liu, Chundi, Lv, Lingyan, Pan, Jinhuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331187/ https://www.ncbi.nlm.nih.gov/pubmed/30666129 http://dx.doi.org/10.2147/OTT.S187817 |
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