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Competition for Space Induces Cell Elimination through Compaction-Driven ERK Downregulation

The plasticity of developing tissues relies on the adjustment of cell survival and growth rate to environmental cues. This includes the effect of mechanical cues on cell survival. Accordingly, compaction of an epithelium can lead to cell extrusion and cell death. This process was proposed to contrib...

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Detalles Bibliográficos
Autores principales: Moreno, Eduardo, Valon, Léo, Levillayer, Florence, Levayer, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331351/
https://www.ncbi.nlm.nih.gov/pubmed/30554899
http://dx.doi.org/10.1016/j.cub.2018.11.007