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Competition for Space Induces Cell Elimination through Compaction-Driven ERK Downregulation
The plasticity of developing tissues relies on the adjustment of cell survival and growth rate to environmental cues. This includes the effect of mechanical cues on cell survival. Accordingly, compaction of an epithelium can lead to cell extrusion and cell death. This process was proposed to contrib...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331351/ https://www.ncbi.nlm.nih.gov/pubmed/30554899 http://dx.doi.org/10.1016/j.cub.2018.11.007 |