A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus

Lymph- and blood-borne retroviruses exploit CD169/Siglec-1-mediated capture by subcapsular sinus and marginal zone metallophilic macrophages for trans-infection of permissive lymphocytes. However, the impact of CD169-mediated virus capture on retrovirus dissemination and pathogenesis in vivo is unkn...

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Detalles Bibliográficos
Autores principales: Uchil, Pradeep D., Pi, Ruoxi, Haugh, Kelsey A., Ladinsky, Mark S., Ventura, John D., Barrett, Brad S., Santiago, Mario L., Bjorkman, Pamela J., Kassiotis, George, Sewald, Xaver, Mothes, Walther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331384/
https://www.ncbi.nlm.nih.gov/pubmed/30595553
http://dx.doi.org/10.1016/j.chom.2018.11.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331384/
https://www.ncbi.nlm.nih.gov/pubmed/30595553
http://dx.doi.org/10.1016/j.chom.2018.11.011

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