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Diversity of Epigenetic Features of the Inactive X-Chromosome in NK Cells, Dendritic Cells, and Macrophages

In females, the long non-coding RNA Xist drives X-chromosome Inactivation (XCI) to equalize X-linked gene dosage between sexes. Unlike other somatic cells, dynamic regulation of Xist RNA and heterochromatin marks on the inactive X (Xi) in female lymphocytes results in biallelic expression of some X-...

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Detalles Bibliográficos
Autores principales: Syrett, Camille M., Sindhava, Vishal, Sierra, Isabel, Dubin, Aimee H., Atchison, Michael, Anguera, Montserrat C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331414/
https://www.ncbi.nlm.nih.gov/pubmed/30671059
http://dx.doi.org/10.3389/fimmu.2018.03087