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Regulation of RNA editing by RNA-binding proteins in human cells

Adenosine-to-inosine (A-to-I) editing, mediated by the ADAR enzymes, diversifies the transcriptome by altering RNA sequences. Recent studies reported global changes in RNA editing in disease and development. Such widespread editing variations necessitate an improved understanding of the regulatory m...

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Detalles Bibliográficos
Autores principales: Quinones-Valdez, Giovanni, Tran, Stephen S., Jun, Hyun-Ik, Bahn, Jae Hoon, Yang, Ei-Wen, Zhan, Lijun, Brümmer, Anneke, Wei, Xintao, Van Nostrand, Eric L., Pratt, Gabriel A., Yeo, Gene W., Graveley, Brenton R., Xiao, Xinshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331435/
https://www.ncbi.nlm.nih.gov/pubmed/30652130
http://dx.doi.org/10.1038/s42003-018-0271-8