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Mature IgD(low/-) B cells maintain tolerance by promoting regulatory T cell homeostasis

A number of different B cell subsets have been shown to exhibit regulatory activity using a variety of mechanisms to attenuate inflammatory diseases. Here we show, using anti-CD20-mediated partial B cell depletion in mice, that a population of mature B cells distinguishable by IgD(low/-) expression...

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Detalles Bibliográficos
Autores principales: Ray, Avijit, Khalil, Mohamed I., Pulakanti, Kirthi L., Burns, Robert T., Gurski, Cody J., Basu, Sreemanti, Wang, Demin, Rao, Sridhar, Dittel, Bonnie N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331566/
https://www.ncbi.nlm.nih.gov/pubmed/30643147
http://dx.doi.org/10.1038/s41467-018-08122-9