Virucidal nano-perforator of viral membrane trapping viral RNAs in the endosome

Membrane-disrupting agents that selectively target virus versus host membranes could potentially inhibit a broad-spectrum of enveloped viruses, but currently such antivirals are lacking. Here, we develop a nanodisc incorporated with a decoy virus receptor that inhibits virus infection. Mechanistical...

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Detalles Bibliográficos
Autores principales: Kong, Byoungjae, Moon, Seokoh, Kim, Yuna, Heo, Paul, Jung, Younghun, Yu, Seok-Hyeon, Chung, Jinhyo, Ban, Choongjin, Kim, Yong Ho, Kim, Paul, Hwang, Beom Jeung, Chung, Woo-Jae, Shin, Yeon-Kyun, Seong, Baik Lin, Kweon, Dae-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331592/
https://www.ncbi.nlm.nih.gov/pubmed/30643128
http://dx.doi.org/10.1038/s41467-018-08138-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331592/
https://www.ncbi.nlm.nih.gov/pubmed/30643128
http://dx.doi.org/10.1038/s41467-018-08138-1

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