Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia

Under hypoxia, most of glucose is converted to secretory lactate, which leads to the overuse of glutamine-carbon. However, under such a condition how glutamine nitrogen is disposed to avoid over-accumulating ammonia remains to be determined. Here we identify a metabolic flux of glutamine to secretor...

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Detalles Bibliográficos
Autores principales: Wang, Yuanyuan, Bai, Changsen, Ruan, Yuxia, Liu, Miao, Chu, Qiaoyun, Qiu, Li, Yang, Chuanzhen, Li, Binghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331631/
https://www.ncbi.nlm.nih.gov/pubmed/30643150
http://dx.doi.org/10.1038/s41467-018-08033-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331631/
https://www.ncbi.nlm.nih.gov/pubmed/30643150
http://dx.doi.org/10.1038/s41467-018-08033-9

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