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Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia
Under hypoxia, most of glucose is converted to secretory lactate, which leads to the overuse of glutamine-carbon. However, under such a condition how glutamine nitrogen is disposed to avoid over-accumulating ammonia remains to be determined. Here we identify a metabolic flux of glutamine to secretor...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331631/ https://www.ncbi.nlm.nih.gov/pubmed/30643150 http://dx.doi.org/10.1038/s41467-018-08033-9 |