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Transactivation of human endogenous retroviruses by tumor viruses and their functions in virus-associated malignancies

Human endogenous retroviruses (HERVs), viral-associated sequences, are normal components of the human genome and account for 8–9% of our genome. These original provirus sequences can be transactivated to produce functional products. Several reactivated HERVs have been implicated in cancers and autoi...

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Detalles Bibliográficos
Autores principales: Chen, Jungang, Foroozesh, Maryam, Qin, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331641/
https://www.ncbi.nlm.nih.gov/pubmed/30643113
http://dx.doi.org/10.1038/s41389-018-0114-y