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Miro proteins prime mitochondria for Parkin translocation and mitophagy

The Parkinson's disease‐associated protein kinase PINK1 and ubiquitin ligase Parkin coordinate the ubiquitination of mitochondrial proteins, which marks mitochondria for degradation. Miro1, an atypical GTPase involved in mitochondrial trafficking, is one of the substrates tagged by Parkin after...

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Detalles Bibliográficos
Autores principales: Safiulina, Dzhamilja, Kuum, Malle, Choubey, Vinay, Gogichaishvili, Nana, Liiv, Joanna, Hickey, Miriam A, Cagalinec, Michal, Mandel, Merle, Zeb, Akbar, Liiv, Mailis, Kaasik, Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331716/
https://www.ncbi.nlm.nih.gov/pubmed/30504269
http://dx.doi.org/10.15252/embj.201899384