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Novel Coumarin-Containing Aminophosphonatesas Antitumor Agent: Synthesis, Cytotoxicity, DNA-Binding and Apoptosis Evaluation

A series of novel coumarin-containing α-aminophosphonates were synthesized and evaluated for their antitumor activities against Human colorectal (HCT-116), human nasopharyngeal carcinoma (human KB) and human lung adenocarcinoma (MGC-803) cell lines in vitro. Compared with 7-hydroxy-4-methylcoumarin...

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Detalles Bibliográficos
Autores principales: Li, Ya-Jun, Wang, Cai-Yi, Ye, Man-Yi, Yao, Gui-Yang, Wang, Heng-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331810/
https://www.ncbi.nlm.nih.gov/pubmed/26287139
http://dx.doi.org/10.3390/molecules200814791