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Polymorph Impact on the Bioavailability and Stability of Poorly Soluble Drugs

Drugs with low water solubility are predisposed to poor and variable oral bioavailability and, therefore, to variability in clinical response, that might be overcome through an appropriate formulation of the drug. Polymorphs (anhydrous and solvate/hydrate forms) may resolve these bioavailability pro...

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Detalles Bibliográficos
Autores principales: Censi, Roberta, Di Martino, Piera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331817/
https://www.ncbi.nlm.nih.gov/pubmed/26501244
http://dx.doi.org/10.3390/molecules201018759