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Synthesis and Enzymatic Incorporation of Modified Deoxyuridine Triphosphates

To expand the chemical functionality of DNAzymes and aptamers, several new modified deoxyuridine triphosphates have been synthesized. An important precursor that enables this aim is 5-aminomethyl dUTP, whereby the pendent amine serves as a handle for further synthetic functionalization. Five functio...

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Detalles Bibliográficos
Autores principales: Liu, Erkai, Lam, Curtis H., Perrin, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331837/
https://www.ncbi.nlm.nih.gov/pubmed/26213912
http://dx.doi.org/10.3390/molecules200813591