Cargando…
Synthesis and Enzymatic Incorporation of Modified Deoxyuridine Triphosphates
To expand the chemical functionality of DNAzymes and aptamers, several new modified deoxyuridine triphosphates have been synthesized. An important precursor that enables this aim is 5-aminomethyl dUTP, whereby the pendent amine serves as a handle for further synthetic functionalization. Five functio...
Autores principales: | Liu, Erkai, Lam, Curtis H., Perrin, David M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331837/ https://www.ncbi.nlm.nih.gov/pubmed/26213912 http://dx.doi.org/10.3390/molecules200813591 |
Ejemplares similares
-
Synthesis of Polyanionic C5-Modified 2′-Deoxyuridine and 2′-Deoxycytidine-5′-Triphosphates and Their Properties as Substrates for DNA Polymerases
por: Dutson, Claire, et al.
Publicado: (2021) -
Purification, crystallization and preliminary crystallographic analysis of deoxyuridine triphosphate nucleotidohydrolase from Arabidopsis thaliana
por: Bajaj, Mamta, et al.
Publicado: (2007) -
The ability to accumulate deoxyuridine triphosphate and cellular response to thymidylate synthase (TS) inhibition
por: Webley, S D, et al.
Publicado: (2001) -
A densely modified M(2+)-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover
por: Wang, Yajun, et al.
Publicado: (2018) -
Base-Resolution Analysis of
Deoxyuridine at the Genome Scale Based
on the Artificial Incorporation Modified Nucleobase
por: Wang, Yafen, et al.
Publicado: (2021)