Synthesis and Biological Evaluation of Lipophilic 1,4-Naphthoquinone Derivatives against Human Cancer Cell Lines

To examine the effect of hydrophobicity on the anticancer activity of 1,4-naphthoquinone derivatives, a series of compounds bearing a 2-O-alkyl-, 3-C-alkyl- or 2/3-N-morpholinoalkyl group were synthesized and evaluated for their anticancer activity against five human cancer cell lines in vitro. The...

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Detalles Bibliográficos
Autores principales: Wang, Shao-Hung, Lo, Chih-Yu, Gwo, Zhong-Heng, Lin, Hong-Jhih, Chen, Lih-Geeng, Kuo, Cheng-Deng, Wu, Jin-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331847/
https://www.ncbi.nlm.nih.gov/pubmed/26133763
http://dx.doi.org/10.3390/molecules200711994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331847/
https://www.ncbi.nlm.nih.gov/pubmed/26133763
http://dx.doi.org/10.3390/molecules200711994

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