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Synthesis and Pharmacological Evaluation of Novel Benzenesulfonamide Derivatives as Potential Anticonvulsant Agents

A novel series of benzenesulfonamide derivatives containing 4-aminobenzenesul-fonamide and α-amides branched valproic acid or 2,2-dimethylcyclopropanecarboxylic acid moieties were synthesized and screened for their anticonvulsant activities in mice maximal electroshock seizure (MES) and subcutaneous...

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Detalles Bibliográficos
Autores principales: Wang, Zhiming, Li, Jinping, Zeng, Xiao-Dong, Hu, Xian-Ming, Zhou, Xiaoju, Hong, Xuechuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331867/
https://www.ncbi.nlm.nih.gov/pubmed/26404228
http://dx.doi.org/10.3390/molecules200917585