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Polymer-Based Prodrugs: Improving Tumor Targeting and the Solubility of Small Molecule Drugs in Cancer Therapy

The majority of anticancer drugs have poor aqueous solubility, produce adverse effects in healthy tissue, and thus impose major limitations on both clinical efficacy and therapeutic safety of cancer chemotherapy. To help circumvent problems associated with solubility, most cancer drugs are now formu...

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Detalles Bibliográficos
Autores principales: Dragojevic, Sonja, Ryu, Jung Su, Raucher, Drazen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331894/
https://www.ncbi.nlm.nih.gov/pubmed/26690101
http://dx.doi.org/10.3390/molecules201219804