Metal- and Semimetal-Containing Inhibitors of Thioredoxin Reductase as Anticancer Agents

The mammalian thioredoxin reductases (TrxRs) are a family of selenium-containing pyridine nucleotide disulfide oxidoreductases playing a central role in cellular redox homeostasis and signaling pathways. Recently, these selenoproteins have emerged as promising therapeutic targets for anticancer drug...

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Detalles Bibliográficos
Autores principales: Gandin, Valentina, Fernandes, Aristi P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331895/
https://www.ncbi.nlm.nih.gov/pubmed/26184149
http://dx.doi.org/10.3390/molecules200712732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331895/
https://www.ncbi.nlm.nih.gov/pubmed/26184149
http://dx.doi.org/10.3390/molecules200712732

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