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Metal- and Semimetal-Containing Inhibitors of Thioredoxin Reductase as Anticancer Agents
The mammalian thioredoxin reductases (TrxRs) are a family of selenium-containing pyridine nucleotide disulfide oxidoreductases playing a central role in cellular redox homeostasis and signaling pathways. Recently, these selenoproteins have emerged as promising therapeutic targets for anticancer drug...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331895/ https://www.ncbi.nlm.nih.gov/pubmed/26184149 http://dx.doi.org/10.3390/molecules200712732 |