The Curcumin Analogue 1,5-Bis(2-hydroxyphenyl)-1,4-pentadiene-3-one Induces Apoptosis and Downregulates E6 and E7 Oncogene Expression in HPV16 and HPV18-Infected Cervical Cancer Cells

In an effort to study curcumin analogues as an alternative to improve the therapeutic efficacy of curcumin, we screened the cytotoxic potential of four diarylpentanoids using the HeLa and CaSki cervical cancer cell lines. Determination of their EC(50) values indicated relatively higher potency of 1,...

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Detalles Bibliográficos
Autores principales: Paulraj, Felicia, Abas, Faridah, Lajis, Nordin H., Othman, Iekhsan, Syed Hassan, Sharifah, Naidu, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331910/
https://www.ncbi.nlm.nih.gov/pubmed/26132907
http://dx.doi.org/10.3390/molecules200711830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331910/
https://www.ncbi.nlm.nih.gov/pubmed/26132907
http://dx.doi.org/10.3390/molecules200711830

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