Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists

The EphA2 receptor and its ephrin-A1 ligand form a key cell communication system, which has been found overexpressed in many cancer types and involved in tumor growth. Recent medicinal chemistry efforts have identified bile acid derivatives as low micromolar binders of the EphA2 receptor. However, t...

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Detalles Bibliográficos
Autores principales: Callegari, Donatella, Pala, Daniele, Scalvini, Laura, Tognolini, Massimiliano, Incerti, Matteo, Rivara, Silvia, Mor, Marco, Lodola, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331951/
https://www.ncbi.nlm.nih.gov/pubmed/26393553
http://dx.doi.org/10.3390/molecules200917132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331951/
https://www.ncbi.nlm.nih.gov/pubmed/26393553
http://dx.doi.org/10.3390/molecules200917132

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