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Highly Stable Tetra-Phenolato Titanium(IV) Agent Formulated into Nanoparticles Demonstrates Anti-Tumoral Activity and Selectivity

Titanium(IV) complexes exhibit high potential as anti-tumor agents, particularly due to their low intrinsic toxicity and cytotoxicity toward cisplatin resistant cells. Nevertheless, Ti(IV) complexes generally undergo rapid hydrolysis that previously hampered their utilization as anticancer drugs. We...

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Detalles Bibliográficos
Autores principales: Meker, Sigalit, Braitbard, Ori, Margulis-Goshen, Katrin, Magdassi, Shlomo, Hochman, Jacob, Tshuva, Edit Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331959/
https://www.ncbi.nlm.nih.gov/pubmed/26473816
http://dx.doi.org/10.3390/molecules201018526